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Image Search Results
Journal: International Journal of Molecular Sciences
Article Title: GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice
doi: 10.3390/ijms22052532
Figure Lengend Snippet: Lysosomal integral membrane protein type B (LIMP2) in Npc1 −/− liver and U18666A treated HEPG2 cells; ( A ) Western blot analysis of LIMP2 in lysates of Npc1 +/+ and Npc1 −/− mouse liver; ( B ) phase contrast microscopy pictures of HEPG2 cells treated with NPC1-inhibitor U18666A (magnification of 63×); ( C ) GCase in HEPG2 lysates was labelled with GCase-specific ABP and subsequently visualized by fluorescence scanning after SDS-PAGE. LIMP2 was analyzed by Western blotting of the same wet gel slab as described in the Materials and Methods section.
Article Snippet: For ,
Techniques: Western Blot, Microscopy, Fluorescence, SDS Page
Journal: International Journal of Molecular Sciences
Article Title: GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice
doi: 10.3390/ijms22052532
Figure Lengend Snippet: Immunohistochemistry NPC liver; “Composite” panels of immunostaining of Npc1 +/+ and Npc1 −/− liver of 80-day-old mice. The first three panels show IBA1, cathepsin D, and LAMP1 in yellow and LIMP2 in magenta. The last panel shows LAMP1 in yellow and cathepsin D in magenta. Brightfield scans were analyzed using spectral imaging; separate images are displayed in heat-map intensity scale. Scale bar = 50 µm.
Article Snippet: For ,
Techniques: Immunohistochemistry, Immunostaining, Imaging
Journal: International Journal of Molecular Sciences
Article Title: GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice
doi: 10.3390/ijms22052532
Figure Lengend Snippet: Immunofluorescence of LIMP2 and bile salt efflux pump (BSEP) in hepatocytes of Npc1 +/+ and Npc1 −/− liver. Scale bar = 20 µm.
Article Snippet: For ,
Techniques: Immunofluorescence